Does a single instruction to a jury need to be considered in the context of the overall charge?

MultiRegion, United States of America

The following excerpt is from United States v. Caronia, 703 F.3d 149 (2nd Cir. 2012):

Cupp v. Naughten, 414 U.S. 141, 14647, 94 S.Ct. 396, 38 L.Ed.2d 368 (1973) ( [A] single instruction to a jury may not be judged in artificial isolation, but must be viewed in the context of the overall charge.).

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